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Operation Midnight Climax was a CIA mind-control research program that began in the 1950's. The project consisted of CIA-run safehouses in San Francisco, Marin and New York. It was established in order to study the effects of LSD on unconsenting individuals. Prostitutes on the CIA payroll were instructed to lure clients back to the safehouses, where they were given a wide range of substances, including LSD and monitored behind two-way mirrors. These experiments were filmed.